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DermatologistsBlog.com Interview: The management of Psoriasis through Diet

The management of psoriasis through diet.

Gleison Duarte
Dermatologist. Master in Sciences of Health.

Gleison Duarte

DermatologistsBlog.com? What are the main findings of the study?

Dr. Duarte: This review focuses specially on the importance of a low-calorie  diet,  with  or without  weight  loss. Besides its adjuvant  role  in  managing psoriasis, it also increases rates of response to treatment with cyclosporine or biological.

As we know, fatty tissue acts as an active endocrine tissue and gives rise to a pro-inflammatory state in overweight patients. Functional foods must be better evaluated in studies. Fish oil and omega-3 supplementation are the most associated with clinical improvement.

DermatologistsBlog.com?  Were any of the findings unexpected?

Dr. Duarte:  Surprisingly, we observed that the role of diet in other immunomodulated diseases, such as Leishmaniasis, in which a protein-energy deficient diet could  favor the  spread  of  intracellular  parasites.

DermatologistsBlog.com?  What should clinicians and patients take away from this study?

Dr. Duarte: Although healthy lifestyle and a low-calorie diet are recommended for most patients with psoriasis, gluten-free diet should be introduced only in those with symptomatic or asymptomatic (positive antibodies to gliadin, or anti-endomysial  and  anti-transglutaminase antibodies). it is recommended that patients with moderate to severe psoriasis or palmoplantar pustulosis be subjected to autoantibody screening.

The message for patients includes a  rich,  varied,  alcohol-restricted,  and  low-calorie diet or low-glycemic index food enriched diet. Antioxidants supplementation could be replaced for the intake of fruits and vegetables. Other suggestions are based in the American Heart Association suggestions for a healthy diet: avoid salt, eat fish twice a week, choose high-fiber foods and minimize intake of partially hydrogenated fat.

DermatologistsBlog.com?  What recommendations do you have for future research as a result of your study?

Dr. Duarte: Specific supplementations, like zinc, vitamin D, folic acid, as well as many suggested functional food should be better studied.

Folic acid supplementatinos, specially, as it is associated with side-efects, and may cause overexposure in people living in countries in which the fortification of flour is mandatory, such as the United States, Canada, and the United Kingdom.

Citation:

The management of psoriasis through diet

Gleison Duarte1  Luan Oliveira Barbosa2  Maria Elisa A Rosa1

1Dermatology Division, Alergodermoclin, Salvador, Bahia, Brazil; 2Escola Bahiana de Medicina e Saúde PúblicaSalvador, Bahia, Brazil

Psoriasis: Targets and Therapy 2012:2 45–53

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