DermatologistsBlog.com eInterview with Dr. Joseph F. Merola, MD Assistant Program Director, Combined Internal Medicine-Dermatology Residency Training Program Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts; Instructor, Harvard Medical School DermatologistsBlog.com: What are the main findings of the study? Dr. Merola: Among patients with systemic lupus (SLE) , those with discoid lupus as part of [...]
All posts in category Connective Tissue Disease
Study: Cancer drug Gleevec™ (imatinib) may be useful in Scleroderma treatment
A drug approved to treat certain types of cancer has shown promising results in the treatment of patients with scleroderma, according to results from an open-label Phase II trial. While the drug’s efficacy must be demonstrated in a Phase III trial, the gold standard for testing a drug, researchers are optimistic that Gleevec™ (imatinib) could [...]
Posted by admin on March 23, 2012
http://dermatologistsblog.com/connective-tissue-disease/study-cancer-drug-gleevec-imatinib-may-be-useful-in-scleroderma-treatment/
Link between Autoimmune Diseases & Poor-Healing Wounds
WASHINGTON, DC — Millions of Americans suffer from wounds that don’t heal, and while most are typically associated with diabetes, new research has identified another possible underlying cause – autoimmune diseases. The finding, published online Dec. 14th in the International Wound Journal, represents an unappreciated link that could lead to important new insights in wound [...]
Posted by admin on December 15, 2011
http://dermatologistsblog.com/wound-care/link-between-autoimmune-diseases-poor-healing-wounds/
Etanercept (Enbrel) helped some dermatomyositis patients wean off steroids
A multicenter pilot study of etanercept for treatment of dermatomyositis found no major safety concerns and many patients treated with the drug were successfully weaned from steroid therapy. These results are encouraging, but larger studies are needed to further investigate the safety and efficacy of etanercept. Results of this clinical trial are available in Annals [...]
Posted by admin on June 17, 2011
http://dermatologistsblog.com/connective-tissue-disease/dermatomyositis/etanercept-enbrel-helped-some-dermatomyositis-patients-wean-off-steroids/
Underlying mechanisms of skin hardening syndromes Elucidated
(Boston) – Researchers from Boston University School of Medicine (BUSM) have discovered new details about the underlying mechanisms of skin hardening syndromes. The team connected pharmacological properties of the Novartis Pharma AG drug called balicatib to the skin disorder for the first time after investigating adverse reactions suffered by patients participating in a clinical trial [...]
Posted by admin on May 17, 2011
http://dermatologistsblog.com/connective-tissue-disease/underlying-mechanisms-of-skin-hardening-syndromes-elucidated/
Study: Raynaud’s attacks reduced in frequency by Sildenafil
DermatologistsBlog.com Editor’s Note: Raynaud’s phenomenon is characterized by sensitivity to cold, particularly of the hands and feet. The fingers and toes may undergo color changes due to vasoconstriction (decrease in blood flow), marked by red, white and purple changes of the digits. The reaction is reversible with warming. Raynaud’s can be found in healthy individuals, [...]
Posted by admin on March 8, 2011
http://dermatologistsblog.com/raynauds/study-raynauds-attacks-reduced-in-frequency-by-sildenafil/
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National Eczema Association
