All posts in category Author Interviews

Psychological Burden in Neurofibromatosis Patients

Psychological Burden in Adult Neurofibromatosis Type 1 Patients: Impact of Disease Visibility on Body Image Interview: Sofia Granström What are the main findings of the study? Disfigurement, mainly through visible neurofibromas, affects most adults with NF1 (a tumor suppressor gene disorder). This esthetic burden is often associated with psychological burden. In this study we found that body [...]

A Pilot Study of Apremilast for Atopic Dermatitis

A Pilot Study of an Oral Phosphodiesterase Inhibitor (Apremilast) for AtopicDermatitis in Adults. Authors’ Interview: Aman Samrao, MD, Eric Simpson MD Background: Apremilast is a novel oral phosphodiesterase type IV (PDE4) inhibitor. Inhibition of PDE4 causes accumulation of intracellular cyclic adenosine monophosphate (cAMP), resulting in inhibition of pro-inflammatory cytokine transcription, neutrophil degranulation, chemotaxis, and adhesion to endothelial cells. Our objective was to obtain preliminary safety and efficacy [...]

Skin Cancer in the Metabolic Syndrome

Metabolic risk factors and skin cancer in the Metabolic Syndrome and Cancer Project (Me-Can)  Author Interview: Dr. Gabriele  Nagel Institute of Epidemiology and Medical Biometry, Ulm University, Helmholtzstr. 22, 89081 Ulm, Germany Agency of Preventive Medicine, Bregenz, Austria What are the main findings of the study? Mechanisms linked to blood pressure may be involved in [...]

Acne Therapy: Adherence and Text Messages

Do automated text messages increase adherence to acne therapy? Results of a randomized, controlled trial. Author Interview: Andreas Boker, M.D What are the main findings of the study? Compliance with topical medications for treatment of acne is lower than previously reported. It appears as if automated electronic reminders in the form of text messages do not enhance compliance with [...]

Genome-wide association study for Vitiligo

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo Author Interview : Richard A. Spritz, M.D. Professor and Director, Human Medical Genetics and Genomics Program University of Colorado School of Medicine, Aurora, CO 80045 USA What are the main findings of the study? Dr. Richard Spritz and colleagues conducted a genome-wide association study of generalized vitiligo [...]

GSTP1 rs1695 polymorphism in Melanoma

Role of glutathione S-transferases in melanoma susceptibility: association with GSTP1 rs1695 polymorphism Author Interview: Gloria Ribas Investigadora “FIS Miquel Servet” Fundacion Investigacion Clinico de Valencia Instituto de Investigacion Sanitaria INCLIVA Av. Blasco Ibanez, 17 46010 Valencia What are the main findings of the study? Glutathione S-transferases (GSTs) GSTM1, GSTT1 and GSTP1 are multifunctional enzymes involved in the detoxification of a [...]

Skin manifestations of athletes competing in the summer olympics

Skin Manifestations of Athletes Competing in the Summer Olympics: What a Sports Medicine Physician Should Know. Author Interview: Jacqueline De Luca MD University of Hawaii Transitional Residency Program, Honolulu, HI, USA. What are the main findings of the study? Athletes competing in the summer Olympics are frequently affected with skin problems related to their sport [...]

Superior Outcome of Women with Melanoma

Superior Outcome of Women With Stage I/II Cutaneous Melanoma: Pooled Analysis of Four European Organisation for Research and Treatment of Cancer Phase III Trials Author Interview Arjen Joosse, Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherland What are the main findings of the study? The basic finding in the article is that [...]

Keratoacanthoma: Clinical and histopathologic features of regression

Keratoacanthoma: Clinical and histopathologic features of regression Author Interview: Christine J. Ko, MD, 333 Cedar St, PO Box 208059, New Haven, CT 06520 What are the main findings of the study? Although keratoacanthoma may be a subtype of squamous cell carcinoma with a very good prognosis (spontaneous regression), and while keratoacanthoma can be histopathologically indistinguishable from [...]

Psoriasis: PSORS2 is Due to Mutations in CARD14

Psoriasis affecting the skin and nails

  Author Interview: Anne M. Bowcock, Ph.D. Professor, Genetics, Pediatrics, Internal Medicine Co-Director Division of Human Genetics     What are the main findings of the study? We identified a gene (CARD14) that is mutated in some rare familial forms of psoriasis, and also identified a pediatric patient with pustular psoriasis with a de novo (sporadic) germline mutation in this [...]