All posts in category Atopic Dermatitis – Eczema

A Pilot Study of Apremilast for Atopic Dermatitis

A Pilot Study of an Oral Phosphodiesterase Inhibitor (Apremilast) for AtopicDermatitis in Adults. Authors’ Interview: Aman Samrao, MD, Eric Simpson MD Background: Apremilast is a novel oral phosphodiesterase type IV (PDE4) inhibitor. Inhibition of PDE4 causes accumulation of intracellular cyclic adenosine monophosphate (cAMP), resulting in inhibition of pro-inflammatory cytokine transcription, neutrophil degranulation, chemotaxis, and adhesion to endothelial cells. Our objective was to obtain preliminary safety and efficacy [...]

Research on Major Allergen from House Dust Mite : Author Interview

Retagging Identifies Dendritic Cell-specific Intercellular Adhesion Molecule-3 (ICAM3)-grabbing Non-integrin (DC-SIGN) Protein as a Novel Receptor for a Major Allergen from House Dust Mite Author Interview: Amir Ghaem-Maghami   MD, PhD Associate Professor in Immunology Course Director for MSc in Immunology & Allergy Immunology, School of Molecular Medical Sciences Queen’s Medical Centre Nottingham University What are the main [...]

Prevalence of eczema and food allergy is associated with latitude in Australia: Dr. Osborne

Author Interview: Nicholas J. Osborne, PhD European Centre for Environment and Human Health, Peninsula College of Medicine and Dentistry, University of Exeter, Truro, United Kingdom Murdoch Childrens Research Institute, Melbourne, Australia Department of Paediatrics, University of Melbourne, Melbourne, Australia What are the main findings of the study? The main findings of the study was that eczema, [...]

Activation of Eosinophils Interacting with Dermal Fibroblasts by Pruritogenic Cytokine IL-31 and Alarmin IL-33: Implications in Atopic Dermatitis : Dr. Wong

Activation of Eosinophils Interacting with Dermal Fibroblasts by Pruritogenic Cytokine IL-31 and Alarmin IL-33: Implications in Atopic Dermatitis. Author Interview: Dr. CK Wong Professor Department of Chemical Pathology The Chinese University of Hong Kong Prince of Wales Hospital Shatin, NT  Hong Kong What are the main findings of the study? This experimental study evaluated the novel immunopathological [...]

Effectivenss of Acupressure on Pruritus & Lichenification Associated with Atopic Dermatitis : Author Interview Dr. Lio

Effectiveness of acupressure on pruritus and lichenification associated with atopic dermatitis: a pilot trial Author Interview: Peter Lio, MD Assistant Professor of Clinical Dermatology & Pediatrics Northwestern University Feinberg School of Medicine What are the main findings of the study? Patients who performed acupressure to the point Large Intestine 11 (LI11; located near the antecubital fossa [...]

Coenzyme A in Mother’s Milk & Atopic Dermatitis : Author Interview : Sho Matsushita, MD, PhD.

Author Interview: Sho Matsushita, MD, PhD. Coenzyme A contained in mothers’ milk is associated with the potential to induce atopic dermatitis What are the main findings of the study? The main findings of this study are that: i) some mothers whose children develop atopic dermatitis within 6 months after birth often demonstrate a higher Th2 [...]

Coenzyme A in Mother’s Milk & Atopic Dermatitis : Author Interview Dr. Matsushita

Coenzyme A contained in mothers’ milk is associated with the potential to induce atopic dermatitis. Author Interview: Sho Matsushita, MD, PhD. Saitama Medical University JAPAN What are the main findings of the study? The main findings of this study are that: i) some mothers whose children develop atopic dermatitis within 6 months after birth often [...]

Author Interview: Dr. Juan Rivera – Mast Cell Interleukin-2 Production Contributes to Suppression of Chronic Allergic Dermatitis

Author Interview: Juan Rivera, M.Sc., Ph.D. Mast Cell Interleukin-2 Production Contributes to Suppression of Chronic Allergic Dermatitis Juan Rivera, M.Sc., Ph.D. Deputy Scientific Director Chief, Laboratory of Molecular Immunogenetics & Molecular Immunology Section National Institutes of Arthritis and Musculoskeletal and Skin Diseases National Institutes of HealthBuilding 10, Room 13C103 Bethesda, Maryland USA  20892-1930 What are [...]

Author Interview: Dr. Jonathan I. Silverberg – Association Between Atopic Dermatitis and Obesity in Adulthood

Author Interview:  Jonathan I. Silverberg, MD, PhD, MPH Association Between Atopic Dermatitis and Obesity in Adulthood What are the main findings of the study? Previous studies found that obesity in early childhood is associated with increased atopic dermatitis (AD). We examined whether obesity in adulthood is also associated with risk of AD using a cross-sectional [...]

Skin contact with food allergens and Atopic Dermatitis

Atopic dermatitis is a form of eczema that is caused by an inappropriate inflammatory response in the skin. Many children with atopic dermatitis also have food allergies, and skin contact with food allergens can make their atopic dermatitis worse. It is unclear why this occurs, but it has been suggested that immune cells known as [...]